Protein Molecular Weight Markers
ProteinSimple iCE280/iCE3 pI Marker 9.77, 200ul
markers for pI determination that will give you both consistent and accurate measurement of isoelectric point on your iCE system. They can be used for whole-column and single-point capillary isoelectric focusing (cIEF) detection to measure your sample protein's isoelectric point, and for quality control of sample analysis. You'll get 200 µL of pI marker stock solution in every vial.
ABclonal Technology GTPBP8 Rabbit pAb
Predicted to enable GTP binding activity and metal ion binding activity. Located in mitochondrion.
ABclonal Technology SLC6A9 Rabbit pAb
The amino acid glycine acts as an inhibitory neurotransmitter in the central nervous system. The protein encoded by this gene is one of two transporters that stop glycine signaling by removing it from the synaptic cleft.
ABclonal Technology GPR32 Rabbit pAb
This gene is intronless and encodes a member of the G-protein coupled receptor 1 family. The encoded protein binds to resolvin D1 and lipoxin A4 and has been linked to pulmonary inflammation. A related pseudogene has been identified on chromosome 19.
ABclonal Technology DDX6 Rabbit pAb
This gene encodes a member of the DEAD box protein family. The protein is an RNA helicase found in P-bodies and stress granules, and functions in translation suppression and mRNA degradation. It is required for microRNA-induced gene silencing. Multiple alternatively spliced variants, encoding the same protein, have been identified.
ABclonal Technology EPN2 Rabbit pAb
This gene encodes a protein which interacts with clathrin and adaptor-related protein complex 2, alpha 1 subunit. The protein is found in a brain-derived clathrin-coated vesicle fraction and localizes to the peri-Golgi region and the cell periphery. The protein is thought to be involved in clathrin-mediated endocytosis. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.
ABclonal Technology ABI1 Rabbit pAb
This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10,11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14.
ABclonal Technology CENPB Rabbit pAb
This gene product is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. The DNA binding domain recognizes and binds a 17-bp sequence (CENP-B box) in the centromeric alpha satellite DNA. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies.
Sigma Aldrich Fine Chemicals Biosciences fluorescent IEf-Marker pI
filtered through a 0.45 mum membrane filter
ABclonal Technology Phospho-IGF-IReceptorβ(Tyr1135/1136)/InsulinReceptorβ(Tyr1150/1151) Rabbit pAb
This gene encodes a member of the receptor tyrosine kinase family. The preproprotein is processed into alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands activates the insulin signaling pathway, regulating glucose uptake, release, and the synthesis and storage of carbohydrates, lipids, and proteins. Mutations in this gene cause inherited severe insulin resistance syndromes, such as type A insulin resistance syndrome, Donohue syndrome, and Rabson-Mendenhall syndrome. The receptor also binds insulin-like growth factor and has tyrosine kinase activity. It plays a critical role in transformation events and is overexpressed in malignant tissues, acting as an anti-apoptotic agent. Alternative splicing produces multiple transcript variants encoding distinct isoforms.
ABclonal Technology DOK4 Rabbit pAb
Predicted to be involved in positive regulation of MAPK cascade and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to act upstream of or within nervous system development. Predicted to be located in cytosol. Predicted to be active in cytoplasm.
S2 Media 15x100mm Chameleon™ COLOREX™ VRE (RUO), 10/pack
Chameleon™ COLOREX™ VRE (RUO) is a selective and differential chromogenic medium used for the qualitative direct detection of VanA/VanB Vancomycin Resistant Enterococcus (VRE). Test specimens include rectal swabs and stools. For Research Use Only (RUO). Not for use in diagnostic procedures unless Laboratory Developed Test (LDT) validation with the product has been completed. Further identification, susceptibility testing, and epidemiological typing should be performed on suspect colonies.• Product meets CLSI performance criteria.• Chameleon™ COLOREX™ VRE should be used by trained professionals within a laboratory setting. • For in vitro diagnostic (IVD) use.• Product is not intended for use in the diagnosis or treatment of disease or other human conditions.
S2 Media 15x100mm Chameleon™ COLOREX™ Serratia, 10/pack
Chameleon™ COLOREX™ Serratia is a selective and differential, chromogenic culture medium used for the qualitative direct detection Serratia marcescens. Media can be utilized for prevention and control of Serratia marcescens within intensive care units (ICU), notably neo-natal. Test specimens include rectal swabs, throat swabs, wound swabs, and stools. It can also be utilized in hygiene and environmental monitoring of surfaces. Further identification, susceptibility testing, and epidemiological typing should be performed on suspect colonies.• Product meets CLSI performance criteria.• Chameleon™ COLOREX™ Serratia should be used by trained professionals within a laboratory setting. • For in vitro diagnostic (IVD) use.• Product is not intended for use in the diagnosis or treatment of disease or other human conditions.
BPS Bioscience Inc AP1 eGFP Reporter Lentivirus (JNK Signaling Pathway), 500 µl x 2
The Activator protein 1 (AP1) eGFP Reporter Lentiviruses are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types of mammalian cells, including primary and non-dividing cells. The particles contain an eGFP gene driven by an AP1 response element located upstream of the minimal TATA promoter (Figure 1). After transduction, activation of the JNK signaling pathway and AP1-mediated activity in the target cells can be monitored by eGFP expression.
Sigma Aldrich Fine Chemicals Biosciences VivaspinR 500 50 kDa MWCO
Designed for fast nondenaturing concentration of biological samples by membrane ultrafiltration. Up to 30-fold concentration of the sample can be achieved with recovery of the target molecule typically exceeding 95%.Vivaspin(R) sample concentrators are designed for fast nondenaturing concentration of biological samples by membrane ultrafiltration. Up to 30-fold concentration of the sample can be achieved with recovery of the target molecule typically exceeding 95%. The entire process is performed in a single tube with an upper compartment containing sample and lower compartment separated by a semipermeable membrane with a molecular weight cut-off (MWCO) selected by the user. Centrifugation is applied to force solvent through the membrane leaving a more concentrated sample in the upper chamber.Vivaspin(R) sample concentrators cater for sample volumes from 100 mul to 20 ml with a range of molecular weight cutoff values from Mr 3 000 to 100 000. for maximum recovery select a MWCO at